
Nucleofill Treatment: True Skin Regeneration at Skinvie
What Is Polynucleotides?
Reveal a new you with the revolutionary power of polynucleotide treatment. Nucleofill, a highly purified polynucleotide derived from salmon, offers a non-filler solution to boost collagen and restore volume loss. Discover the science behind this cutting-edge skin booster, which stimulates natural hydration, the generation of fibroblasts and collagen synthesis. Experience remarkable results addressing various skin concerns, from dark circles to wrinkles, for a rejuvenated and radiant you.
BOOK APPOINTMENTAt a glance
No of Sessions
2-3 Sessions
Procedure
30 Mins
Recovery
3-5 Days
Results Duration
6-7 months after the first 90 days

What Are Polynucleotides?
Nucleofill is a non-filler treatment designed to boost collagen and restore volume loss. Polynucleotides are fragmented DNA molecules that, when injected into the skin, attract water and improve blood supply, particularly to collagen-producing cells.
Polynucleotides act as a powerful hydrating agent by drawing water to the skin, enhancing moisture retention. This hydration supports skin regeneration and rejuvenation and results in a plumper and more youthful appearance.
They stimulate the production of essential components like collagen, hyaluronic acid and elastin within the skin’s cells. By promoting the generation of fibroblasts, they play a crucial role in improving skin elasticity and firmness.

What Is Nucleofill Used For?
The efficacy and safety of polynucleotides have been extensively studied and supported by scientific evidence. Clinical research has demonstrated remarkable results in addressing multiple common concerns such as sunken tear troughs and acne scarring.
One single session typically lasts around 30 minutes and 2-3 sessions are recommended, spaced three weeks apart, to achieve optimal outcomes. Pain during treatment is minimal, with slight stinging occurring during injections. Our amazing team will help to keep you comfortable throughout your appointment.
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Why Nucleofill Is The Gold Standard
Unlike traditional skin boosters, polynucleotides offer non-filler treatment options for collagen and volume restoration. Their unique properties provide natural-looking results without the need for artificial fillers and we use the best product available for this – Nucleofill.
Polynucleotides are a scientifically advanced and effective approach for treating various skin concerns compared to other aesthetic treatments. Their ability to stimulate the skin’s natural production of essential substances sets them apart from many other treatments.

What To Expect From Your Treatment
Unlike instant results seen with dermal fillers, polynucleotides exhibit distinct behaviour. Transformation occurs at a cellular level taking around 6 weeks (2 sessions 3 weeks apart) to reveal a more refreshed, youthful complexion. You will not see any lumps or overfilling concerns, but no instant boost either. Multiple sessions lead to the ultimate payoff – the skin you have been longing for.
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What Concerns Do Polynucleotides Treat?
Dark circles
Sunken tear troughs
Sagging skin under the eyes
Rosacea
Acne scarring
Loss of volume
Wrinkles on the face, neck, inner arms and thighs
The Procedure
Injections into targeted areas with minimal pain. This procedure is approximately 30 minutes long.
The Results
As previously mentioned, this unique treatment takes 90 days for optimal results to materialise.
Aftercare
This is a minimally-disruptive procedure, with no significant downtime required. Our experts recommend that you avoid exercise, saunas, steam rooms, sun beds and hot baths for 24 hours to reduce the risk of bruising and swelling. It is also important to keep the treatment area clean in order to avoid infection, which is why we also recommend avoiding makeup for 24 hours and taking care not to touch your skin.
What Areas Can Be Treated With Nucleofill?
Although Nucleofill can be used to treat practically any area of the body, the most popular are the face and the neck.
How Does Nucleofill Work?
Nucleofill is an injectable biorevitalisation procedure composed of polynucleotides that deeply hydrate, stimulate collagen production, contour and tighten the skin. The polynucleotides work to reduce free radical damage while also moisturising and boosting collagen levels.
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Featured In
Skinvie Medical Aesthetics and Dr Anna Puri are both regularly featured in leading publications and recommended by notable public figures.
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